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Study quantifies faulty gene's role in ovarian cancer risk

January 19, Study quantifies faulty gene's role in ovarian cancer risk Intermediate magnification micrograph of a low malignant potential LMP mucinous ovarian tumour.

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The micrograph shows: Simple mucinous epithelium right and mucinous epithelium that pseudo-stratifies left - diagnostic of a LMP tumour. Epithelium in a frond-like architecture is seen at the top of image. The gene variant had already been linked to cancer of the ovaries, but the size of the additional risk has now been quantified in a study in the Journal of the National Cancer Institute.

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The fault inhibited tissue cells from properly repairing their own DNA, causing genetic damage to build up over time, and leading to cancer, said the team. The rare but deadly disease, with few early symptoms, is often diagnosed at a very advanced stage, hence its reputation as a silent killer. About 60 percent of patients die within five years.

Diéta a prosztatarák kockázatának csökkentése és a kezelési eredmények javítása érdekében Best treatment for high risk prostate cancer. Principal inclusion criteria 1. Patients prematurely best treatment for high risk prostate cancer planned frontline therapy for reasons other than disease progression are not considered high risk.

There is no standard or routine test for early detection of ovarian cancer—a process known as "screening" to boost survival chances by allowing for treatment to begin as soon as possible after disease onset. The study compared the genes of over 8, European women—including a group diagnosed with ovarian cancer, a healthy group, and a third with a family history of the disease.

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They found that women who carried the BRIP1 mutation were more likely to be diagnosed with an aggressive form of cancer, at a later stage and at an older age.

This would be important in a disease like ovarian cancer, which tends to be diagnosed at a later stage when the chances of survival are worse.

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Those diagnosed with the variant is found, can opt to surgically remove their breasts and ovaries in order to lower their risk. Ovarian cancer is the seventh most common cancer in women worldwide, withnew cases diagnosed inaccording to the World Cancer Research Fund International. Explore further.

High-Risk Prostate Cancer: Hormone Therapy after Surgery - Ask a Prostate Expert, Mark Scholz, MD

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